By train:
From the north Milano-Firenze (Santa Maria Novella) Firenze-Foligno;
From the south Roma-Foligno.At Foligno station there will be (on request) an our car.

By car:
From the north motorway A1 way out Val di Chiana ( in direction of Perugia). After Perugia, continue for Foligno, then on the way for Fano there will be Valtopina.
From the south motorway A1 way out Orte. Then turn into government way Flaminia in direction of Fano; way out Valtopina.

See the map